Lquin 500mg Tablet contains Levofloxacin 500mg, an antibiotic belonging to the fluoroquinolone class. It is used for selected bacterial infections affecting different parts of the body, depending on the susceptibility of the infecting organism and the clinical indication.

Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes involved in DNA replication, transcription, repair, and recombination. This interferes with bacterial growth and can ultimately result in bacterial cell death.

The 500mg strength does not mean that 500mg is appropriate for every infection or every patient. The prescribed dose and duration depend on the infection being treated, the causative organism, kidney function, age, and other clinical factors.

Important

Levofloxacin belongs to a fluoroquinolone class associated with potentially serious adverse reactions, including tendon injury or rupture, peripheral neuropathy, central nervous system effects, QT prolongation, severe allergic reactions, and severe diarrhea associated with C. difficile. Use should therefore follow the prescribing healthcare professional’s instructions.

Product Information

Uses of Lquin 500mg

Levofloxacin may be prescribed for certain susceptible bacterial infections, including:

• Respiratory tract infections
• Certain community-acquired bacterial pneumonia cases
• Selected urinary tract infections
• Certain kidney infections
• Selected skin and soft-tissue infections
• Other susceptible bacterial infections when clinically appropriate

The exact indication should be determined by the prescribing healthcare professional.

Lquin 500mg should not be used for viral infections, such as:

• Common cold
• Influenza
• Most viral sore throats

Unnecessary antibiotic use contributes to antimicrobial resistance.

How Lquin 500mg Works

Levofloxacin targets two important bacterial enzymes:

1. DNA gyrase
2. Topoisomerase IV

These enzymes are required for bacterial DNA replication and maintenance.

By inhibiting these enzymes, levofloxacin interferes with bacterial DNA processes and prevents susceptible bacteria from multiplying and surviving.

Dosage and Administration

The appropriate dose depends on the infection and the patient’s clinical condition.

Lquin 500mg should be taken exactly as prescribed.

Important considerations include:

• Take the tablet with water.
• It may generally be taken with or without food.
• Take doses at approximately the same time each day when using a regular schedule.
• Complete the prescribed course unless your healthcare professional instructs you otherwise.
• Do not take an additional dose to compensate for a missed dose without following the prescribed instructions.
• Kidney impairment may require dose adjustment.

Mineral and Antacid Separation

Do not take levofloxacin at the same time as products containing:

• Aluminium
• Magnesium
• Iron
• Zinc
• Certain mineral supplements
• Sucralfate

These products can reduce levofloxacin absorption. Follow the separation interval specified by your healthcare professional or product information.