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Hetrazan 100mg Tablet – Diethylcarbamazine 100mg
Hetrazan 100mg Tablet contains Diethylcarbamazine (DEC) 100mg, an antiparasitic medicine used primarily for the treatment of certain filarial worm infections. It works by affecting susceptible filarial parasites and altering their surface and metabolic processes, helping the immune system eliminate them.
Diethylcarbamazine may be prescribed for conditions such as lymphatic filariasis, tropical pulmonary eosinophilia, and certain other filarial infections. The dosage and duration depend on the infection, body weight, and clinical circumstances.
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Hetrazan 100mg Tablet contains Diethylcarbamazine Citrate (DEC), a synthetic antiparasitic medicine of the piperazine class. It has been used extensively in the treatment of filarial infections, including infections caused by susceptible Wuchereria, Brugia, and related filarial parasites.
Diethylcarbamazine has activity primarily against microfilariae and can also have activity against adult filarial worms in some infections. Its precise mechanism is not completely understood, but it appears to alter parasite surface properties and arachidonic-acid-related processes, making the parasites more susceptible to immune-mediated elimination.
It is important to distinguish diethylcarbamazine from general deworming medicines: DEC is specifically associated with treatment of susceptible filarial and certain other parasitic infections.
Product Information
| Attribute | Details |
|---|---|
| Brand Name | Hetrazan 100mg |
| Generic Name | Diethylcarbamazine |
| Strength | 100mg |
| Dosage Form | Tablet |
| Drug Class | Antifilarial / Antiparasitic |
| Prescription Status | Prescription Required |
| Route | Oral |
| Primary Action | Acts against susceptible filarial parasites |
Uses of Hetrazan 100mg
Diethylcarbamazine may be prescribed for certain susceptible parasitic infections, including:
- Lymphatic filariasis
- Tropical pulmonary eosinophilia
- Certain filarial infections
- Some other tissue nematode infections when specifically indicated
The exact indication depends on the parasite involved and the clinical diagnosis.
How Hetrazan 100mg Works
The precise mechanism of diethylcarbamazine is not completely established.
It appears to:
- Alter the surface properties of susceptible filarial parasites.
- Interfere with parasite arachidonic-acid metabolism.
- Increase the susceptibility of microfilariae to immune-mediated clearance.
- Reduce the number of circulating microfilariae.
This helps the body’s immune system remove susceptible parasites.
Dosage and Administration
The 100mg tablet strength is not itself a universal treatment dose.
Diethylcarbamazine dosing varies according to:
- Type of parasitic infection
- Patient’s body weight
- Age
- Severity of infection
- Treatment objective
- Clinical guidelines
A healthcare professional should determine the appropriate daily dose and treatment duration.
Administration
- Take exactly as prescribed.
- Take with food if recommended by your healthcare professional, particularly if gastrointestinal upset occurs.
- Swallow with water.
- Follow the prescribed treatment schedule.
- Do not take additional tablets without medical advice.
- Complete the prescribed course unless your healthcare professional instructs otherwise.
| Pills | 100, 200, 400, 600, 800, 1000 |
|---|
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