RYBELSUS 14MG contains semaglutide 14mg, a GLP-1 receptor agonist that helps regulate blood glucose and appetite.

Semaglutide mimics the activity of naturally occurring GLP-1. It increases insulin secretion when blood glucose is elevated, reduces glucagon secretion and slows gastric emptying. These effects help improve glycemic control and may reduce food intake and body weight.

The 14mg strength is generally used as a higher maintenance dose, following dose escalation from lower strengths when appropriate and tolerated.

Product Information

Uses

RYBELSUS 14MG may be prescribed to improve blood glucose control in adults with:

• Type 2 diabetes mellitus
• Elevated blood glucose requiring pharmacological treatment

It is used together with appropriate diet and physical activity.

Semaglutide may also reduce appetite and food intake and may result in weight loss in some patients.

RYBELSUS is not insulin and is not indicated for the treatment of type 1 diabetes.

How Semaglutide Works

Semaglutide activates GLP-1 receptors and:

• Increases insulin secretion when blood glucose is elevated
• Reduces glucagon secretion when blood glucose is elevated
• Slows gastric emptying
• Influences appetite and food intake

These effects improve glucose regulation and can contribute to reduced food intake and body weight.

Dosage

RYBELSUS treatment generally begins with 3mg once daily.

After the initial treatment period, the dose may be increased to 7mg once daily. If additional glycemic control is required and the 7mg dose is tolerated, it may subsequently be increased to 14mg once daily.

RYBELSUS 14MG should only be reached through the prescribed dose-escalation schedule. Do not start directly with 14mg unless specifically instructed by a healthcare professional.

How to Take RYBELSUS 14MG

Proper administration is important because oral semaglutide has specific absorption requirements.

• Take once daily.
• Take it on an empty stomach when you first wake up.
• Take it with no more than approximately 120 mL (4 ounces) of plain water.
• Swallow the tablet whole.
• Do not split, crush or chew it.
• Wait at least 30 minutes before eating, drinking anything other than plain water, or taking other oral medicines.

Weight-Management Information

Semaglutide can influence appetite and food intake and may result in weight loss.

Possible effects include:

• Reduced appetite
• Increased feeling of fullness
• Reduced food intake
• Slower gastric emptying
• Reduction in body weight in some patients

Individual results vary.